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Kinase Inhibitor Library

Why Screen?

Identifying signaling pathways or targets ● Antiestrogen resistance is a major problem in breast cancer treatment.   ● Dr. CW Yde’s lab performed a kinase inhibitor screening on an antiestrogen responsive cell line using the SelleckChem kinase inhibitor library. Compound JNJ-7706621, an inhibitor of aurora kinase, exhibited growth inhibition of antiestrogen-resistant cell lines.   ● This discovery identified protein aurora kinase as a new target in treatment of antiestrogen-resistant breast cancer.

About Kinase Inhibitor Library

Description & Advantages Product Citations Best Selling Libraries ● Unique collection of 429 kinase inhibitors for HTS and HCS   ● Numerous FDA-approved Inhibitors Nature, 2015,520(7547),368-72 Nature, 2015,517(7534),391-5 Nature, 2014,510(7504),283-7 Nature, 2014,508(7494),118-22 ● FDA approved Drug Library ● Bioactive Compound Library ● Anti-cancer Compound Library ● Cherry Pick Library

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