Home Signaling Pathway Screening Library Catalog

Bioactive Compound Library

Description & Advantage Product Citations Best-Selling Libraries ● Unique collection of 2659   compounds for HTS and HCS ● Numerous FDA approved inhibitors ● Bioactivity and safety confirmed by   preclinical research and clinical trials Nature, 2015;16:520(7547):368-72 Nature, 2015 Jan 15; 517(7534):391-5 Nat Cell Biol, 2015 Jan; 17(1):57-67 Nat Med, 2014 Aug; 20(8):954-60 Nature, 2014 Jun 12; 510(7504):283-7 ● Inhibitor library ● Kinase inhibitor library ● FDA-approved drug library ● Express-pick library ● Cherry Pick library

Why Screen?

Screening for modulators of target proteins ● Induced pluripotent stem cell systems are at the forefront of new treatment methodologies in both the lab and the clinic.   ● Induction often requires the use of factors, especially Oct4, to establish pluripotency but is inefficient and carries risks of genetic mutation and abnor-mal expression.   ● Dr. Deng’s Lab designed an OCT-4 GFP reporter system and identified a known chemical forskolin (activator of adenylyl cyclase) that is able to reproduce the effects of OCT-4. By using forskolin in conjunction with other chemicals, they successfully induced pluripotent stem cells without the use of factor.

Customize Your Library

You can select:

Specific Compounds   Quantities   Plate Map   Format (solid or DMSO solution)

Facility Partners

Tel: +1-832-582-8158 Fax: +1-832-582-8590 Email: [email protected] Add: 9330 Kirby drive, STE 200 Houston, TX 77054 USA. Tel: +49-89-46148500 Fax: +49-89-461485022 Email: [email protected] Add: Karl-Schmid-Str. 14, 81829 Munich, Germany.