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| The first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM in cell-free assays, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation. |
| Related Products: BEZ235, Pictilisib, CAL-101 |
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| AktInhibitor |
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| A highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. Phase 2. |
| Related Products: Perifosine, GSK690693, AZD5363 |
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| mTORInhibitor |
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